Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 95 |
Director, Development Strategy & Operations
Cambridge, Massachusetts
Overview The Director, Development Strategy, Operations, & Portfolio role will be focused on delivering the near- and long-term objectives of the R&D Leadership Team as Alnylam delivers the next wave of transformational medicines. Reporting...
4h
| Job Type | Full Time |
Director, Strategic Account Lead - Northern California
Cambridge, Massachusetts
Overview The Strategic Account Lead (SAL) roleleads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizingaccess toAl...
4h
| Job Type | Full Time |
Associate Director, Statistical Genetics
Cambridge, Massachusetts
Overview The Alnylam Human Genetics (AHG) team is looking for an Associate Director to lead our large-scale statistical genetics capability through direct, hands-on technical contributions and strategic guidance. The successful candidate wi...
1d
| Job Type | Full Time |
Sr. QA Specialist, Raw Material Quality
Cambridge, Massachusetts
Overview Reporting to the Associate Director of Raw Material Quality, this individual will be responsible for ensuring GMP compliance of raw material management activities internally and externally for Alnylam's pipeline.Summary of Key Resp...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a highly motivated and creative scientific leader to join our Next Wave, Target Discovery and Validation team. Our mission is to discover novel genetically informed targets and experime...
1d
| Job Type | Full Time |
Patient Education Liaison - Rare Disease (Southeast Region)
Cambridge, Massachusetts
Overview Reporting to the Director, US Patient Services, the Patient Education Liaison (PEL) is a critical component of the product brand commercial strategy and works in close coordination with Field Sales, Field Reimbursement, Patient Ser...
1d
| Job Type | Full Time |
Sr. Director, U.S. Commercial and Marketing Technology
Cambridge, Massachusetts
Location: Cambridge, MA (Hybrid role; 3 days/week onsite) Reports to: Executive Director, Commercial & Development Technologies Overview Alnylam is the world's leading RNA interference (RNAi) company, pioneering the development of novel the...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: Alnylam is seeking a progressive, dynamic, business-focused HR Business Partner to support several Commercial leaders and their teams. Reporting to the VP HR, Commercial, this HR Business Partner will play a key role in delivering...
2d
| Job Type | Full Time |
Senior Director, IT Finance Leader
Cambridge, Massachusetts
Overview: We are seeking a strategic, results-driven IT leader to own the technology vision and execution for Finance. This leader will serve as a crucial bridge between technical capabilities and strategic business needs, partnering direct...
2d
| Job Type | Full Time |
Principal Associate Scientist, Biology
Cambridge, Massachusetts
Overview We are seeking a highly motivated and skilled Principal Associate Scientist to join our innovative Research & Development (ReDev) team focused on advancing next-generation oligonucleotide-based therapeutics. The ideal candidate wil...
2d
| Job Type | Full Time |