Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 169 |
Senior Associate Scientist, Ligand Discovery
Cambridge, Massachusetts
Overview: The Delivery Sciences team at Alnylam is seeking a Senior Associate Scientist to contribute to our ligand discovery efforts for expanding RNAi delivery to all tissues. The successful candidate will help drive in vitro ligand selec...
4h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The Next Wave Biology group is seeking a motivated candidate to fill an Associate Scientist II position to join our dynamic, fast-paced and interdisciplinary team. This position is an opportunity to potentially see one's work prog...
4h
| Job Type | Full Time |
Director, Clinical Data Management
Cambridge, Massachusetts
Summary The Director, Clinical Data Management is responsible for the oversight of data management activities in support of Alnylam studies across all stages of clinical drug development. This position reports to the head of the Clinical Da...
4h
| Job Type | Full Time |
Associate Director, Laboratory Informatics Platforms
Cambridge, Massachusetts
Alnylam is seeking a strategic and delivery-oriented technology leader to serve as Associate Director, Laboratory Informatics Platforms. This role is responsible for the delivery, evolution, and operational stewardship of core laboratory in...
4h
| Job Type | Full Time |
Director, Cyber Defense Principal Engineer
Cambridge, Massachusetts
Overview Alnylam is pioneering RNAi therapeutics and scaling rapidly across research, development, and global commercialization. The Director, Cyber Defense will play a critical role in designing and advancing our next-generation cyber defe...
4h
| Job Type | Full Time |
Cambridge, Massachusetts
Role Summary The Brand Director, Global Marketing Rare is responsible for defining and driving the global brand strategy for OXLUMO and GIVLAARI, ensuring alignment from global vision through local execution. This role leads cross-functiona...
4h
| Job Type | Full Time |
Associate Director, Clinical Operations
Cambridge, Massachusetts
Overview The Associate Director is responsible for leading a team of Global Trial Leaders and Trial Managers within the Study Management Organization. The position is responsible for staff development and study oversight, and will work clos...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
The Director is accountable for the operational execution of the Clinical Development Plan (CDP). As a disease area thought partner, the Director is responsible for the development of the program-level operational strategy and ensuring cros...
1d
| Job Type | Full Time |
Director, Global New Product Commercialization, Metabolic
Cambridge, Massachusetts
Overview We are seeking a strategic, forward-thinking leader to join our team in a newly created Product Planning role. This individual will play a critical role in shaping the long-term commercial vision of our pipeline assets-integrating ...
1d
| Job Type | Full Time |
Associate Director, Field Systems and Technology
Cambridge, Massachusetts
Role Summary The Associate Director, Field Systems & Technology enables field teams to effectively execute by ensuring fieldfacing systems-primarily CRM and related tools-are intuitive, aligned to field workflows, and clearly understood. Re...
1d
| Job Type | Full Time |