Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 21 - 30 of 95 |
Senior Director Biostatistics Head of Statistical Innovation & Methodology
Cambridge, Massachusetts
Senior Director Biostatistics, Head of Statistical Innovation & Methodology Overview At Alnylam, the Senior Director Biostatistics, Head of Statistical Innovation & Methodology will provide scientific leadership in advanced statistical meth...
5h
| Job Type | Full Time |
Senior Associate Scientist, Lab Automation Engineering
Cambridge, Massachusetts
Overview We seek a passionate, experienced, and creative Lab Automation Scientist or Engineer to drive implementation of automated and robotic solutions across our drug discovery platform. The candidate will become an integral member of a m...
5h
| Job Type | Full Time |
Senior Associate Scientist, Investigative Sciences
Cambridge, Massachusetts
Overview: The Investigative Sciences team within the Early Development Department at Alnylam is seeking a highly motivated and experienced Senior Associate Scientist to join an interdisciplinary team dedicated to expanding the reach of RNAi...
5h
| Job Type | Full Time |
Senior Associate Scientist, Delivery Technology
Cambridge, Massachusetts
Overview: The Research Department at Alnylam is seeking a motivated and skilled Senior Associate Scientist to join our innovative targeted delivery team. The successful candidate will provide critical hands-on support for ligand discovery p...
5h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: Alnylam's Translational Research group is seeking a highly motivated Metabolomics Scientist to join our team. We use untargeted and targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based omics and computational b...
5h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The mission ofDMPKis to enable efficient and successful drug discovery and development of siRNA and other therapeutic candidates by characterizing and interpreting ADME (absorption, distribution, metabolism, and excretion) and PK/...
5h
| Job Type | Full Time |
Scientist, Antibody Conjugation
Cambridge, Massachusetts
Overview We are seeking a Scientist to join our Protein Sciences group to help with our antibody conjugation efforts. The candidate must be independent, goal oriented, technically competent, and able to work efficiently across multiple proj...
5h
| Job Type | Full Time |
Norton, Massachusetts
Quality Site Head (Norton) Overview The Quality Site Head will lead the Quality organization for the Norton Manufacturing and Testing Facility. This role serves as the senior Quality leader for the site, accountable for building and sustain...
5h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The successful candidate will be part of a team responsible for understanding the disposition mechanisms and pharmacokinetic/pharmacodynamic (PK/PD) relationships of oligonucleotide therapeutics and other emerging modalities. The ...
5h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The Principal Medical Writer(equivalent to Associate Director) represents medical writing on multi-disciplinary teams, collaborates on the development of clinical documents in accordance with all applicable regulations, Good Clini...
5h
| Job Type | Full Time |