Postdoctoral Position in Dr. Michael J. Betenbaugh's Lab

Are you excited to explore a yet-to-be-solved problem at the heart of recombinant adeno-associated virus (rAAV) manufacturing? Join Michael Betenbaugh's research lab to develop and mature some of the most in-demand research skills in academia and industry today.

We are seeking a highly motivated and skilled Postdoctoral Researcher to join our dynamic research team. The successful candidate will lead a project focused on improving production of rAAV using the Sf9/recombinant baculovirus (rBV) and HEK-293 expression system to achieve higher yields of high-quality and functionally active rAAV by applying computational modelling and complementary analytical and molecular biology techniques. A Ph.D. in Chemical Engineering, Biological Sciences, Bioengineering, or a related field is desired.

• Johns Hopkins offers an unmatched environment for life sciences research, with a dynamic community in biomolecular engineering, biophysics, biochemistry, and medicine.
• Standard benefits
• Baltimre is one of the most affordable and livable cities on the US East Coast
• The Betenbaugh laboratory offers unmatched opportunities to collaborate with industrial partners in the biopharma and biotech industry
• Be part of the AMBIC biomanufacturing center (Prof. Betenbaugh serves as the Center Director), and you will be able to participate in AMBIC Conferences, workshops, and seminars.
• Lab alumni have advanced to positions in industry giants (Genentech, Merck, Pfizer, GSK), and recent startups (Drul, Biolinco).
• Initial appointment period of one year, with expectation of 2 or more years total.
• Supportive mentoring environment, with regular 1:1 meetings with Dr. Betenbaugh

More information about the Betenbaugh Lab at: https://www.betenbaughlab-jhu.com/

Key responsibilities could include, but are not limited to, assisting in the following:

• Conduct literature reviews on rAAV production technologies, computational modeling, and advanced analytical techniques.

- Design and perform experiments to evaluate strategies for optimizing rAAV production.

• Develop and/or apply computational models to identify and address bottlenecks in the rAAV manufacturing process.
• Perform data analysis and interpretation to guide experimental and computational efforts.

- Prepare and present research findings through journal articles, conference presentations, and internal reports.

• Maintain detailed documentation of experimental and computational workflows, results, and methodologies. Communicate results with industrial collaborators
• Assist in mentoring graduate students and junior researchers on the team.

• PhD in Chemical Engineering, Biological Sciences, Bioengineering, or a related field
• Background in molecular biology, virology, and protein expression helpful
• Capacity to manipulate baculovirus and rAAV t

- Advanced microscopy, mathematical modeling, and machine learning techniques.

- Proficiency in data analysis, statistical modeling, and experimental design.

Ability to work collaboratively in a multidisciplinary team environment.

In Interfolio, applicants should upload a CV, cover letter detailing their research experience and interests, and contact information for three references. The statement should state why the Betenbaugh lab is a good fit for your career trajectory.

Salary Range

The referenced salary range represents the minimum and maximum salaries for this position and is based on Johns Hopkins University's good faith belief at the time of posting. Not all candidates will be eligible for the upper end of the salary range. The actual compensation offered to the selected candidate may vary and will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, internal equity, market conditions, education/training and other factors, as reasonably determined by the University.

Total Rewards

Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/.

Equal Opportunity Employer

The Johns Hopkins University is committed to equal opportunity for its faculty, staff, and students. To that end, the university does not discriminate on the basis of sex, gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status or other legally protected characteristic. The university is committed to providing qualified individuals access to all academic and employment programs, benefits and activities on the basis of demonstrated ability, performance and merit without regard to personal factors that are irrelevant to the program involved.

Pre-Employment Information

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Background Checks

The successful candidate(s) for this position will be subject to a pre-employment background check including education verification.

EEO is the Law:

https://www.eeoc.gov/sites/default/files/2023-06/22-088_EEOC_KnowYourRights6.12ScreenRdr.pdf

Diversity and Inclusion

The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion.

Vaccine Requirements

Johns Hopkins University strongly encourages, but no longer requires, at least one dose of the COVID-19 vaccine. The COVID-19 vaccine does not apply to positions located in the State of Florida. We still require all faculty, staff, and students to receive the seasonal flu vaccine. Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. This change does not apply to the School of Medicine (SOM). SOM hires must be fully vaccinated with an FDA COVID-19 vaccination and provide proof of vaccination status. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/.

The following additional provisions may apply, depending upon campus. Your recruiter will advise accordingly. The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.