ASSOCIATE DIRECTOR/DIRECTOR- BIOLOGICS

ABOUT US:

Calibr-Skaggs Institute for Innovative Medicines was founded on the principle that the creation of new medicines can be accelerated by pairing world-class biomedical research with state-of-the-art drug discovery and development capabilities. Calibr-Skaggs is a division of Scripps Research, a first-of-its-kind, nonprofit translational research institute dedicated to creating the next generation of medicines. Scripps Research is ranked the most influential institution in the world for its impact on innovation. Our educational and training programs mold talented and committed students and postdocs into leading-edge scientists. Leveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. We expand basic knowledge in the biosciences and use these fundamental advancements to develop profound innovations that improve wellbeing. Calibr-Skaggs' drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age-related and degenerative diseases. If you have a passion for making a difference, this is your opportunity to join our transformative team.

POSITION TITLE: Associate Director/ Director Biologics

POSITION SUMMARY:

Calibr-Skaggs is seeking exceptional candidates for the role of Associate Director or Director on our Biologics team who will help translate potentially transformative therapies into first-in-human clinical studies-a critical step to bringing new medicines to patients. Specifically, this position will be responsible for the development of a portfolio of biologics programs focused on immunology and oncology from concept to IND submission. Modalities of focus include monoclonal antibodies, Mult specific antibodies, antibody-drug conjugates, fusion proteins, and enzymes. The Associate Director will lead these programs in partnership with the protein sciences team and will work closely with our highly experienced translational team including pharmacology, toxicology, CMC (chemistry, manufacturing, and controls), and clinical groups. This Associate Director or Director will also work closely with other internal and external stakeholders to critically evaluate data, present programs, and review new opportunities. In addition, the Associate Director will have the opportunity to engage with other teams at Calibr-Skaggs including medicinal chemistry and cell biology groups to collaborate on a wide range of programs in infectious and neglected tropical diseases, metabolic disorders, neurological conditions, and other rare disease indications. Endless opportunities await those who join our team.

The Associate Director will serve an integral role in Calibr-Skaggs' highly engaging and collaborative ecosystem developed within Scripps Research Institute and will be encouraged to engage in the seamless flow of ideas within and between the institutes. The ideal candidate is expected to bring with them the proficiencies listed below and can expect to receive world-class training in translational medicine at Calibr-Skaggs. Candidates with experience in antibody engineering, drug discovery, assay development, and in vivo models who are looking to take the next steps in their career and join a high-impact team are encouraged to apply. This position offers significant growth opportunity through promotion structures designed to retain exceptional talent within the Calibr-Skaggs team.

DUTIES & RESPOSNSIBILITIES:

• Manage and lead a portfolio of biologics programs
• Design, generate, and develop antibody-based programs
• Evaluate, initiate, and develop projects through IND-enabling studies
• Review, prepare, analyze, interpret, and present data to key stakeholders
• Evaluate and stay on top of competitive landscape to strategically position programs for success
• Critically evaluate new opportunities to initiate new programs
• Author manuscripts and poster presentations to disseminate publicly
• Author relevant IND sections for late-stage programs
• Maintain budgets and timelines for programs within the portfolio
• Manage FTE effort across programs within the portfolio

KEY COMPETENCIES:

• Excellent verbal, written, and interpersonal communication skills - including proficiency in scientific terminology and writing skills
• Experience in antibody discovery research is important
• Exceptional data analysis abilities, and proficiency with relevant software is expected
• Good understanding of statistical principles and methods
• Experience with GLP/GMP is helpful but not required
• Adaptable / Flexible - willing and able to adjust to multiple demands and shift priorities as well as an ability to meet day-to-day challenges with confidence and professionalism
• Proficient critical thinking, problem-solving, decision-making skills and an exceptional commitment to quality

REQUIRED QUALIFICATIONS:

• Master's degree with 10+ years' experience or PhD with 6+ years' experience in industry
• Must have industry experience in drug development / drug discovery

PHYSICAL REQUIREMENTS:
This position works in a laboratory environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.