Senior Manager, Patient Affairs

How will your role help us transform hope into reality?

As Senior Manager, Patient Affairs, you will play a key role in delivering Blueprint's patient engagement efforts in systemic mastocytosis (SM) and related mast cell diseases. Working closely with cross-functional partners and external advocacy groups, you will help implement core programs and support the successful execution of non-promotional initiatives aligned with U.S. launch goals.

This role focuses on translating strategy into action-managing initiatives that elevate disease awareness, strengthen community relationships, and ensure the patient voice is reflected across internal and external engagements.

Success requires strong project management, cross-functional coordination, and an ability to work at both the tactical and strategic interface of advocacy and internal execution. You will serve as a critical conduit between external advocacy partners and internal teams, translating insights into action and ensuring our initiatives remain grounded in the real-world experiences of the patients we serve.

From guidng our Colors of SM campaign, to managing corporate funding governance, to ensuring compliant, strategic patient engagement, you will be a central force in convening for purpose with tangible, measurable progress for the communities we serve.

Compliance and regulatory adherence are crucial aspects of this opportunity. The Senior Manager will articulate business rationale and ensure compliance with the U.S. and International Promotional Review Board (PRB), collaborating with legal and compliance teams to develop and implement relevant policies and procedures.

What will you do?

Strategic Program Execution

• Lead, manage, and support Blueprint's key Patient Affairs initiatives, such as the Colors of SM campaign, as directed in collaboration with advocacy groups and internal stakeholders.
• Help ensure alignment across Patient Affairs activities and broader enterprise objectives by supporting workstreams in disease awareness, patient education, and support programming.
• Develop advocacy landscape assessments that identify key stakeholders, trends, and opportunities for engagement.
• Represent Blueprint Medicines at external events, such as patient advocacy meetings, advisory boards, industry meetings, and events.
• Collaborate with cross-functional teams, including Medical Affairs, Clinical Development, Clinical Operations, Corporate Communications, and others, to ensure continued incorporation of community insights into strategy and decision-making.

Operational & Project Management

• Provide project management for key initiatives across U.S. and international efforts, including timelines, budget tracking, and status reporting.
• Support the development of community-facing materials, including newsletters, handouts, and videos.
• Develop and track key metrics to assess the impact and effectiveness of advocacy initiatives.
• Optimize use of resources to ensure efficient and timely delivery of programs that drive measurable community benefit.

Corporate Funding Stewardship

• Manage Blueprint's corporate funding portal, review committee operations, and associated processes.
• Partner with legal, compliance, and vendors to ensure requests are reviewed in a timely, compliant, and consistent manner.
• Oversee tracking, documentation, and reporting of funding activities to maintain transparency and accountability.

Compliance & Governance

• Ensure all patient engagement and advocacy initiatives comply with U.S. and international regulations and internal policies.
• Partner with Compliance and Legal on PRB submissions, contracts, and policy development relevant to Patient Affairs programming.
• Provide business rationale and documentation for patient engagements, funding, and collaborative programs.

Internal Collaboration

• Work closely with the Senior Director of patient experience and community engagement to integrate patient perspectives into planning and execution.
• Support internal teams with best practices for engaging advocacy partners and understanding patient community needs.
• Support the delivery of internal education and culture-building efforts that elevate awareness of the patient experience.

External Engagement & Representation

• Develop and maintain trusted relationships with patient advocacy organizations, community leaders, and professional groups.
• Represent the Patient Affairs team at advocacy forums, conferences, and community meetings, ensuring Blueprint is seen as a credible, trusted partner as directed.
• Bring the patient voice into relevant internal conversations, helping ensure our decisions reflect lived experience.

Other responsibilities as assigned, in support of Patient Affairs goals and evolving business needs.

What minimum qualifications do we require?

• Bachelor's degree in public health, nursing, life sciences, communications, or a related field
• Ability to travel up to 30%, including domestic and international travel.
• 6+ years of proven experience in patient advocacy within industry or nonprofit settings

What additional qualifications will make you a stronger candidate?

• Demonstrated success in navigating regulatory and legal compliance related to advocacy efforts.
• Deep understanding of commercialization and R&D, including experience with commercial product launches.
• Proven Leadership in Cross-Functional Teams
• Experience in allergy/immunology other rare disease or oncology experience.
• Excellent communication, collaboration, and leadership skills to effectively engage cross-functional teams, patients, and external stakeholders.
• Agile, strategic leader adept at navigating fast-paced environments, shifting priorities, and ambiguity to drive patient-centered impact and measurable outcomes.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators - the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it.

Patients are waiting. Are you ready to make the leap?

Equity, Diversity, Inclusion, and Affirmative Action

At Blueprint Medicines, wefoster an environment of fair treatment and full participationforall of our employees as we navigate complex challenges in pursuing our mission to improve the lives of patients. We celebrate our unique differences and varied career and life experiences so that we can sustain our diverse culture and ensure everyone feels accepted. We arecommitted to non-discrimination, equal employment opportunity, as well as an inclusive recruitment process. We consider all qualified applicants based on merit and without regard to race, color, sex, gender identity, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable federal or state law.

We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com. We are also an E-Verify Employer. For more information, please see ourEEOPolicy Statement, theE-Verify Participation Poster, theRight to Work Poster, and theEEOKnow Your Rights Poster.

Blueprint Medicines, a Sanofi company, is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients' lives by solving important medical problems, with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines, including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in theU.S.andEurope. Leveraging our established research, development, and commercial capability and infrastructure, we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors. For more information, visitwww.BlueprintMedicines.comand follow us onX(formerly Twitter; @BlueprintMeds) andLinkedIn.